7110935

Tocris Bioscience™ Montelukast sodium

CysLT1 and GPR17 antagonist

Manufacturer: Fischer Scientific

CAS Number: 151767-02-1

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Chemical Name or Material

1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt

Target

Leukotriene and Related Receptor Antagonists

Formula Weight

608.17

CAS

151767-02-1

Molecular Formula

C35H35ClNNaO3S

Purity

>99%

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Description

  • Cysteinyl leukotriene receptor 1 (CysLT1) and GPR17 antagonist
  • Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice
  • Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats
  • Orally active and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature