7146020
Tocris Bioscience™ PF 04449913 maleate
Potent Smo antagonist
Manufacturer: Fischer Scientific
CAS Number: 2030410-25-2
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Chemical Name or Material
1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
Synonym
glasdegib, PF-913
Purity
98%
CAS
2030410-25-2
Molecular Formula
C21H22N6O.C4H4O4
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ PF 04449913 maleate | -- | ₹ 11,046.68 | ||
Tocris Bioscience™ PF 04449913 maleate | -- | ₹ 43,257.56 | ||
2030410-25-2 | 1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)ureamaleatesalt | -- | -- |
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Description
- Potent Smo antagonist (IC50 = 5 nM)
- Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model
- Also eliminates self-propagation capacity of AML cells.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C