7180126
Tocris™ BAY 87-2243
Mitochondrial complex I inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1227158-85-1
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Chemical Name or Material
1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
CAS
1227158-85-1
Molecular Formula
C26H26F3N7O2
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris™ BAY 87-2243 | -- | ₹ 8,989.00 | ||
Tocris™ BAY 87-2243 | -- | -- | ||
Medchemexpress LLC HY-15836 10mg , BAY 87-2243 CAS:1227158-85-1 Purity:>98% | -- | ₹ 12,615.75 | ||
Apexbio Technology LLC BAY 87-2243, 50mg. Cas: 1227158-85-1 MFCD: MFCD28143915. HIF-1 inhibitor,potent and selective | -- | ₹ 46,547.00 | ||
Selleck Chemical LLC BAY 87-2243 10mg 1227158-85-1 | -- | ₹ 18,903.60 | ||
eMolecules BAY 87-2243 | 1227158-85-1 | MFCD28143915 | 50mg | -- | ₹ 74,002.61 |
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Description
- Exhibits no effect on mitochondrial complex III Induces mitochondrial permeability transition pore (mPTP) opening, stimulates autophagosome formation and mitophagy, and increases ROS levels Activates necroptotic and ferroptotic cell death Also inhibits hypoxia-induced gene activation Induces cell death in melanoma cell lines in vitro and exhibits antitumor activity in a mouse NSCLC xenograft model in vivo
SAFETY INFORMATION
- Recommended Storage : Store at -20°C