7180142
Tocris™ VU 6005649
Positive allosteric modulators of mGlu7 and mGlu8 receptors. Also NK1 antagonist.
Manufacturer: Fischer Scientific
CAS Number: 2137047-43-7
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Chemical Name or Material
3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS
2137047-43-7
Molecular Formula
C16H12F5N3O
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris™ VU 6005649 | -- | ₹ 20,336.50 | ||
Tocris™ VU 6005649 | -- | ₹ 85,618.00 | ||
eMolecules Medchem Express / VU6005649 / 5mg / 446259212 / HY-107982 / / 2137047-43-7 / [null] / 357.284 / C16H12F5N3O | -- | ₹ 9,170.56 | ||
2137047-43-7 | VU6005649 | -- | ₹ 17,978.00 - ₹ 90,691.00 |
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Description
- Positive allosteric modulator of mGlu7 and mGlu8 receptors (EC50 = 0.65 μM and 2.6 μM for mGlu7 and mGlu8, respectively) Displays >3.8 fold selectivity for mGlu7 and mGlu8 over other mGlu receptors (EC50 >10 μM for mGlu1,2,3,4,5,6) Also NK1 receptor antagonist (Ki= 650 nM, IC50 = 3.4 μM) Brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C