7199111
Tocris™ JNJ 10198409
Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
Manufacturer: Fischer Scientific
CAS Number: 627518-40-5
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Chemical Name or Material
N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target
PDGF Receptor Inhibitors
Purity
98%
CAS
627518-40-5
Molecular Formula
C18H16FN3O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris™ JNJ 10198409 | -- | ₹ 28,907.20 | ||
Tocris™ JNJ 10198409 | -- | ₹ 1,20,687.56 | ||
Biotang Inc JNJ-10198409, Free Base, > 99%, 25MG, CAS#627518-40-5, M.W.325.34, PDGF Receptor Tyrosine Kinase Inhibitor IV; RWJ-540973. RS323-25MG | -- | ₹ 83,417.92 | ||
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor IV | -- | ₹ 23,709.60 | ||
Sigma Aldrich Fine Chemicals Biosciences JNJ-10198409 >=98% (HPLC), solid | 627518-40-5 | 1MG | -- | ₹ 26,929.62 | ||
627518-40-5 | N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine | -- | ₹ 2,314.00 - ₹ 11,748.00 |
Related Products
Description
- Potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively)
- Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively)
- Displays antiproliferative activity in multiple tumor cell lines
- Accelerates down regulation of fibroblast genes in reprogramming of human fibroblasts into functional cardiomyocytes, within 9C cocktail.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C