69-761-0

Tocris™ JNJ 10198409

Manufacturer: Fischer Scientific

CAS Number: 627518-40-5

Select a Size

Pack Size SKU Availability Price
Each of 1 69-761-0-Each-of-1 In Stock ₹ 28,907.20

69-761-0 - Each of 1

₹ 28,907.20

In Stock

Quantity

1

Base Price: ₹ 28,907.20

GST (18%): ₹ 5,203.296

Total Price: ₹ 34,110.496

Chemical Name or Material

N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine

Quantity

10 mg

Molecular Formula

C18H16FN3O2

Purity

98%

CAS

627518-40-5

Target

PDGF Receptor Inhibitors

Formula Weight

2273

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Description

  • Potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively)
  • Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively)
  • Displays antiproliferative activity in multiple tumor cell lines
  • Accelerates down regulation of fibroblast genes in reprogramming of human fibroblasts into functional cardiomyocytes, within 9C cocktail.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C