7199114

Tocris™ MMG 11

TLR2 antagonist

Manufacturer: Fischer Scientific

CAS Number: 313254-94-3

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Chemical Name or Material

Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate

Target

Toll-like Receptor Antagonists

Purity

97%

CAS

313254-94-3

Molecular Formula

C15H14O7

Other Options

Image Product Name Manufacturer Price Range
Medchemexpress LLC ethyl 5-[2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl]furan-2-carboxylate | 313254-94-3 | 306.27 g/mol | 10MG
-- ₹ 14,017.50
Tocris™ MMG 11
-- ₹ 17,524.10
Tocris™ MMG 11
-- ₹ 73,336.00

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Description

  • MMG 11 is a TLR2 antagonist (IC50 values are in the range 1.7 - 5.7 μM)
  • Exhibits selectivity for TLR2 over TLR4, TLR5, TLR7/8 and TLR9
  • Reduces TLR2-mediated cytokine secretion from PBMCs
  • MMG 11 preferentially inhibits TLR2/1- over TLR2/6-mediated NK-κB activation (IC50 values are 0.87 and 7.4 μM, respectively).

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C