7222994

Tocris Bioscience™ STX 64

Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II

Manufacturer: Fischer Scientific

CAS Number: 288628-05-7

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Chemical Name or Material

6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate

Target

Hydrolase Inhibitors

Purity

0.98

CAS

288628-05-7

Molecular Formula

C14H15NO5S

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Description

  • STX 64 is a potent steroid sulfatase inhibitor (IC50 = 8 nM)
  • Estrone sulfate-stimulated uterine growth and mammary tumor growth are inhibited by STX 64 in animal models
  • STX 64 shows inhibition of steroid sulfatase activity in peripheral blood lymphocytes, liver and tumor tissues and is active in vivo
  • STX 64 is also a potent inhibitor of carbonic anhydrase II (IC50 = 25 nM).

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C