7250118
Tocris Bioscience™ Capzimin dimer
Selective proteasome inhibitor
Manufacturer: Fischer Scientific
CAS Number: 2084868-04-0
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Chemical Name or Material
8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target
Proteasome Inhibitors
Purity
0.98
CAS
2084868-04-0
Molecular Formula
C30H24N6O2S4
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Capzimin dimer | -- | ₹ 18,479.96 | ||
Tocris Bioscience™ Capzimin dimer | -- | ₹ 77,739.72 | ||
eMolecules Medchem Express / Capzimin / 5mg / 446259818 / HY-110404 / / 2084868-04-0 / [null] / 628.800 / C30H24N6O2S4 | -- | ₹ 19,651.20 | ||
2084868-04-0 | Capzimin | -- | ₹ 7,298.00 - ₹ 58,384.00 |
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Description
- Capzimin dimer is a specific inhibitor of proteasome isopeptidase Rpn11 (IC50 = 2.1 μM and 3.8 μM, in 293T and A549 cell lines, respectively)
- It exhibits 80-fold selectivity for Rpn11 over Csn5, ten-fold over AMSH and six-fold over BRCC36 (IC50 = 30 μM, 4.5 μM, and 2.3 μM, respectively)
- Capzimin dimer blocks proliferation of cancer cells.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C