74-442

Tocris Bioscience™ DA ZP1

Manufacturer: Tocris Bioscience™

CAS Number: 1816254-69-9

Select a Size

Pack Size SKU Availability Price
Each of 1 74-442-Each-of-1 In Stock ₹ 34,265.00

74-442 - Each of 1

₹ 34,265.00

In Stock

Quantity

1

Base Price: ₹ 34,265.00

GST (18%): ₹ 6,167.70

Total Price: ₹ 40,432.70

Chemical Name or Material

3 ',6 '-bis(Acetyloxy)-4 ',5 '-bis[[bis(2-pyridinylmethyl)amino]methyl]-2 ',7 '-dichlorospiro[isobenzofuran-1(3 H),9 '-[9 H]xanthen]-3-one

Quantity

2 mg

Molecular Formula

C50H40Cl2N6O7

CAS

1816254-69-9

Target

Fluorescent Cell Indicators and Sensors

Purity

0.9

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Description

  • DA ZP1 (diacetylated Zinpyr1) is a fluorogenic Zn(II) sensor (Kd Zn2+ = 0.6 nM)
  • It can be used to image and isolate pancreatic β-cells and β-like cells in vitro
  • Used to purify live stem cell-derived β-like cells
  • It can image transplanted islet grafts and endogenous mouse islets in vivo
  • DA ZP1 is non-fluorescent in the absence of Zn(II) ions but its binding with Zn(II) promotes hydrolytic cleavage of the acetyl groups, generating a strong fluorescent signal
  • Excitation and emission maxima (λ) are 490 nm and 522 nm, respectively.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C