75-695-0
Tocris Bioscience™ Verdinexor
Manufacturer: Fischer Scientific
CAS Number: 1392136-43-4
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 75-695-0-Each-of-1 | In Stock | ₹ 80,733.68 |
75-695-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 80,733.68
GST (18%): ₹ 14,532.062
Total Price: ₹ 95,265.742
Chemical Name or Material
(2 Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1 H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide
Quantity
50 mg
Molecular Formula
C18H12F6N6O
CAS
1392136-43-4
Target
Antiviral Compounds
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Verdinexor | -- | -- | ||
Tocris Bioscience™ Verdinexor | -- | ₹ 19,305.88 | ||
Selleck Chemical LLC Verdinexor (KPT-335) 5mg 1392136-43-4 ATG-527 | -- | ₹ 21,039.60 | ||
eMolecules AstaTech / KPT335 / 5mg / 562547058 / 40840 / 95.000 / 1392136-43-4 / MFCD28167840 / 442.325 / C18H12F6N6O | -- | ₹ 39,171.57 |
Related Products
Description
- Verdinexor is a selective exportin-1 (XPO1/CRM1) inhibitor
- It potently inhibits influenza virus ribonucleoprotein (vRNP) export by disrupting XPO1-NEP binding and the replication of influenza virus A and B strains in vitro , including H1N1, H5N1 and H7N9 (IC50 values in the range 40 - 420 nM range)
- Verdinexor limits influenza A virus spread in mouse lung in vivo
- In neuroblastoma, verdinexor suppresses cell proliferation and induces cell apoptosis
- It also induces P53 nuclear accumulation and induces G0/G1 phase cell cycle arrest by activating P53 function
- Verdinexor inhibits tumor growth in in vivo mouse models
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C