81-051-0
Tocris Bioscience™ CAF 382
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 81-051-0-Each-of-1 | In Stock | ₹ 17,961.98 |
81-051-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,961.98
GST (18%): ₹ 3,233.156
Total Price: ₹ 21,195.136
Chemical Name or Material
N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target
CDKL5
Purity
0.98
Quantity
10 mg
Molecular Formula
C16H22N4O2S2.CF3CO2H
Related Products
Description
- CAF 382 is potent and selective CDKL5 (cyclin-dependent kinase-like 5) inhibitor (IC50 = 10 nM)
- Exhibits nearly 100-fold selectivity for CDKL5 over CDKL2, low inhibition for CDKL3 and CDKL4 (IC50 = 2.1-2.7 ?M), and no inhibition for CDKL1
- CAF 382 lacks GSK3β activity
- It causes a significant reduction in pSer222 EB2 at 5 nM without a change in total EB2 levels in rat primary cortical neuron cultures
- CAF 382 is an analog of SNS 032 (Cat
- No
- 4075).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C