7116081
BAY 678
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 675103-36-3
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Chemical Name or Material
5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Assay Percent Range
>98%
Formula Weight
Observed MW: 400.35
CAS
675103-36-3
Molecular Formula
C20H15F3N4O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
BAY 678 | -- | ₹ 39,026.50 | ||
BAY 678 | -- | ₹ 9,798.90 | ||
Sigma Aldrich Fine Chemicals Biosciences BAY-678 >=98% (HPLC) | 675103-36-3 | MFCD29924806 | 5MG | -- | ₹ 12,102.22 | ||
BAY-678 | -- | ₹ 10,356.30 - ₹ 41,625.00 | ||
675103-36-3 | BAY678 | -- | ₹ 3,115.00 - ₹ 7,476.00 |
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Description
- Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM)
- Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases
- Effective in an acute lung injury model in vivo
- Orally bioavailable
- Inactive S-enantiomer (Cat.No.6389) also available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C