SML0939
PFI-3
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1819363-80-8
Synonym(S): (E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML0939-5-MG | In Stock | ₹ 13,619.70 |
| 25 MG | SML0939-25-MG | In Stock | ₹ 54,945.00 |
SML0939 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 13,619.70
GST (18%): ₹ 2,451.546
Total Price: ₹ 16,071.246
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
yellow to orange
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=C(C(/C=C/N2[C@H](C3)CN(C4=NC=CC=C4)[C@H]3C2)=O)C=CC=C1
InChI
1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1
InChI key
INAICWLVUAKEPB-QSTFCLMHSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Ambeed / (E)-1-(2-Hydroxyphenyl)-3-((1R4R)-5-(pyridin-2-yl)-25-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one / 1mg / 552733100 / A455988 / / 1819363-80-8 / MFCD28100807 / 321.380 / C19H19N3O2 | -- | ₹ 3,971.18 | ||
1819363-80-8 | PFI3 | -- | ₹ 2,581.00 - ₹ 1,31,631.00 |
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Description
- Biochem/physiol Actions: SMARCA4 (SWI/SNF related, Matrix associated, Actin dependent Regulator of Chromatin, subfamily A, member 4) is a transcriptional activator and is a component of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. SMARC4 (also known as BRG1) and the related protein SMARCA2 (also known as BRM) contain a bromodomain that is structurally similar to the PolyBromo1 (PB1) 5 bromodomain. PFI-3 is a selective chemical probe for SMARCA bromodomains that inhibits SMARCA2, SMARCA4 and PB1(5) bromodomains. For full characterization details, please visit the PFI-3 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: PFI-3 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable