SML1534
I-BRD9
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1714146-59-4
Synonym(S): N-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML1534-5-MG | In Stock | ₹ 16,486.48 |
| 25 MG | SML1534-25-MG | In Stock | ₹ 63,488.63 |
SML1534 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 16,486.48
GST (18%): ₹ 2,967.566
Total Price: ₹ 19,454.046
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
CCN1C(C2=C(SC(C(NC3CCS(CC3)(=O)=O)=N)=C2)C(C4=CC(C(F)(F)F)=CC=C4)=C1)=O
InChI
1S/C22H22F3N3O3S2/c1-2-28-12-17(13-4-3-5-14(10-13)22(23,24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30,31)9-7-15/h3-5,10-12,15H,2,6-9H2,1H3,(H2,26,27)
InChI key
WRUWGLUCNBMGPS-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ I-BRD9 | -- | -- | ||
Tocris Bioscience™ I-BRD9 | -- | ₹ 27,461.84 | ||
Tocris Bioscience™ I-BRD9 | -- | ₹ 1,13,667.24 | ||
Sigma Aldrich Fine Chemicals Biosciences I-BRD9 >=98% (HPLC) | 1714146-59-4 | MFCD28952791 | 25MG | -- | ₹ 73,303.96 | ||
Selleck Chemical LLC I-BRD9 5mg 1714146-59-4 GSK602 | -- | ₹ 10,359.60 | ||
eMolecules Ambeed / N-(11-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-45-dihydrothieno[32-c]pyridine-2-carboximidamide / 1mg / 552620541 / A178532 / / 1714146-59-4 / MFCD28952791 / 497.550 / C22H22F3N3O3S2 | -- | ₹ 2,695.81 | ||
1714146-59-4 | I-BRD9 | -- | ₹ 1,513.00 - ₹ 12,727.00 |
Related Products
Description
- General description: I-BRD9 is developed from thienopyridone scaffold.[1] It can also be used as an identifier for BRD9 regulated gene in Kasumi-1 cells involved in oncology and immune response pathways.[2]
- Biochem/physiol Actions: I-BRD9 is a selective cellular chemical probe for bromodomain-containing protein 9 (BRD9), thought to be a member of the chromatin remodelling SWI/SNF BAF complex, which plays a fundamental role in gene expression regulation. I-BRD9 has a pIC50 value of 7.3 with greater than 700-fold selectivity over the BET family and 200-fold over the highly homologous bromodomain-containing protein 7 (BRD7) and greater than 70-fold selectivity against a panel of 34 bromodomains. For full characterization details, please visit the I-BRD9 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: I-BRD9 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
- Other Notes: I-BRD9 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the I-BRD9 probe summary on the Chemical Probes Portal website.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable