01-674-553

Protein C Monoclonal Antibody (9072), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-553-Each-of-1 In Stock ₹ 47,570.50

01-674-553 - Each of 1

₹ 47,570.50

In Stock

Quantity

1

Base Price: ₹ 47,570.50

GST (18%): ₹ 8,562.69

Total Price: ₹ 56,133.19

Antigen

Protein C

Classification

Monoclonal

Concentration

7.7 mg/mL

Formulation

50% water with 50% glycerol and no preservative

Gene Accession No.

P33587

Gene Symbols

PROC

Immunogen

Mouse protein C.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Western Blot

Clone

9072

Conjugate

Unconjugated

Gene

PROC

Gene Alias

Activation peptide; Anticoagulant protein C; APC; autoprothrombin IIA; Blood coagulation factor XIV; EDQVDPRLIDGK; inactivator of coagulation factors Va, VIII; PC; prepro-protein C; Proc; PROC1; protein C; protein C (inactivator of coagulation factors Va and VIIIa); protein C prepropeptide; protein C, inactivator of coagulation factors Va and VIIIa; THPH3; THPH4; type I protein C; vitamin K-dependent protein C; Vitamin K-dependent protein C heavy chain; Vitamin K-dependent protein C light chain

Host Species

Rat

Purification Method

Ammonium sulfate precipitation, Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19123

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-43032 detects Protein C in mouse samples
  • MA1-43032 has successfully been used in Western blot and ELISA applications
  • MA1-43032 was derived from mouse protein C
  • Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex
  • Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII
  • Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains
  • The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation
  • The molecular weight of the active enzyme is 55 kDa and the normal concentrations in human plasma is approximately 1-3 ng/mL because of the very fast turnover, the proenzyme concentration is approximately 3 μg/mL
  • Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.