Bax Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-802-Each-of-1 | In Stock | ₹ 46,502.50 |
01-674-802 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Bax
Classification
Polyclonal
Formulation
PBS with 0.08% sodium azide
Gene Accession No.
Q07813
Gene Symbols
BAX
Immunogen
Synthetic peptide corresponding to residues 172 to 199 of Bax.
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Gene
BAX
Gene Alias
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
Host Species
Sheep
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
12028
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis
- Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function
- Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2
- The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain
- Bcl-2 is also expressed in different Isoforms
- Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha
- Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa)
- BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis
- Overexpression of BAX functions to promote cell death
- BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.