01-674-851

SGPL1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-851-Each-of-1 In Stock ₹ 52,510.00

01-674-851 - Each of 1

₹ 52,510.00

In Stock

Quantity

1

Base Price: ₹ 52,510.00

GST (18%): ₹ 9,451.80

Total Price: ₹ 61,961.80

Antigen

SGPL1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SGPL1

Gene Alias

AI428538; D10Xrf456; FLJ13811; hSPL; KIAA1252; mSPL; S1PL; Sgpl1; Spgl1; sphingosine phosphate lyase 1; sphingosine-1-phosphate aldolase; Sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase 1-like protein; spl; SPL 1; SP-lyase 1; zgc:162153

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20397, 286896, 522515, 8879

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

O95470, Q8CHN6, Q8R0X7

Gene Symbols

SGPL1

Immunogen

Synthetic peptide corresponding to sphingosine 1-phosphate lyase 1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • By Western blot, PA1-12722 detects a ∽64 kDa protein representing S1P lyase 1 from MDBK cell lysate
  • Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine
  • Elevates stress-induced ceramide production and apoptosis
  • The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor
  • Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum
  • Sphingosine 1-phosphate lyase is found primarily in the liver and kidney
  • Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.