01-674-849
SPHK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-849-Each-of-1 | In Stock | ₹ 48,905.50 |
01-674-849 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
SPHK1
Classification
Polyclonal
Formulation
PBS with 0.08% sodium azide
Gene Accession No.
Q8CI15, Q91V26, Q9NYA1
Gene Symbols
SPHK1
Immunogen
Synthetic peptide corresponding to the C-terminal of human Sphingosine Kinase 1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Gene
SPHK1
Gene Alias
1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
170897, 20698, 618605, 8877
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- A suggested positive control for this product is MDBK cell lysate
- SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
- S1P signals through G-protein coupled receptors and controls diverse cellular processes
- Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
- SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
- Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
- S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
- The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).