01-675-807

TIRAP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-807-Each-of-1 In Stock ₹ 47,170.00

01-675-807 - Each of 1

₹ 47,170.00

In Stock

Quantity

1

Base Price: ₹ 47,170.00

GST (18%): ₹ 8,490.60

Total Price: ₹ 55,660.60

Antigen

TIRAP

Classification

Polyclonal

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P58753, Q99JY1

Gene Symbols

TIRAP

Immunogen

Synthetic peptide corresponding to 15 residues near the C-terminus of mouse TIRAP.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

TIRAP

Gene Alias

Mal, wyatt

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114609, 117149, 680127

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • A suggested positive control for this product is liver, kidney, spleen, skeletal muscle or heart lysate
  • Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
  • The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4
  • This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.
  • While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known
  • It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.