01-675-805
MD-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-805-Each-of-1 | In Stock | ₹ 46,814.00 |
01-675-805 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,814.00
GST (18%): ₹ 8,426.52
Total Price: ₹ 55,240.52
Antigen
MD-1
Classification
Polyclonal
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O95711, O88188
Gene Symbols
LY86
Immunogen
Synthetic peptide corresponding to 15 residues from near the center of human MD-1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
LY86
Gene Alias
MD-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17084, 291359, 9450
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
- The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4
- This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.
- While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known
- It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.