01-676-538
TLR1 Monoclonal Antibody (GD2.F4), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-538-Each-of-1 | In Stock | ₹ 66,527.50 |
01-676-538 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 66,527.50
GST (18%): ₹ 11,974.95
Total Price: ₹ 78,502.45
Antigen
TLR1
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.
Q15399
Gene Symbols
TLR1
Immunogen
Human TLR1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
GD2.F4
Conjugate
FITC
Gene
TLR1
Gene Alias
CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7096
Content And Storage
4° C, store in dark
Form
Liquid
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Description
- MA1-40168 detects TLR1 from human samples
- The MA1-40168 immunogen is human TLR1
- Positive control: HeLa cells transfected with TLR1 mRNA; Negative control: Mock transfected HeLa cells
- TLR1 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain
- The TLRs could constitute an important and unrecognized component of innate immunity in humans
- In mice, TLR1 interacts with TLR2 and co-expression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide
- They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several tri-acylated lipopeptides
- Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for the TLR1 gene.