14-079-395

CD79b Monoclonal Antibody (CB3-1), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 14-079-395-Each-of-1 In Stock ₹ 3,06,605.00

14-079-395 - Each of 1

₹ 3,06,605.00

In Stock

Quantity

1

Base Price: ₹ 3,06,605.00

GST (18%): ₹ 55,188.90

Total Price: ₹ 3,61,793.90

Antigen

CD79b

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P40259

Gene Symbols

Cd79b

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

974

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Western Blot

Clone

CB3-1

Conjugate

Unconjugated

Gene

Cd79b

Gene Alias

AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7

Host Species

Mouse

Quantity

10 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain
  • Together with the Ig-alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM)
  • CD79b expression is exclusive to B lymphocytes and B cell lymphomas
  • Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface
  • The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation
  • Applications Reported: This CB3-1 antibody has been reported for use in flow cytometric analysis and immunoblotting (WB)
  • Applications Tested: This CB3-1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg)
  • The mIgM component binds antigen and the Ig alpha /I g beta heterodimer tranduces signals.