IL-20RB Monoclonal Antibody (20RNTC), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-120-637-Each-of-1 | In Stock | ₹ 1,22,642.00 |
14-120-637 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,642.00
GST (18%): ₹ 22,075.56
Total Price: ₹ 1,44,717.56
Antigen
IL-20RB
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q6UXL0
Gene Symbols
Il20rb
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
213208, 53833
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
20RNTC
Conjugate
Unconjugated
Gene
Il20rb
Gene Alias
AV228068; DIRS1; Fibronectin type III domain containing 6; FNDC6; Gm186; IL-20 receptor subunit beta; IL20R2; IL-20R2; IL20RB; IL-20RB; IL-20R-beta; interleukin 20 receptor beta; interleukin 20 receptor beta subunit; interleukin 20 receptor subunit beta; interleukin-20 receptor II; interleukin-20 receptor subunit beta; RGD1566151; UNQ557/PRO1114
Host Species
Rat
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
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Description
- Description: This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1
- IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain
- IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24
- IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24
- The IL-20R complex signals primarily via the JAK-STAT pathway
- IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation
- Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi
- Applications Reported: This 20RNTC antibody has been reported for use in immunocytochemistry, immunoblotting (WB) and flow cytometric analysis
- Applications Tested: This 20RNTC antibody has been tested by immunofluorescent staining and flow cytometric analysis of fixed and permeabilized A375 cells
- This can be used between 1-10 μg/mL
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009].