Nkx2.1 Monoclonal Antibody (8G7G3/1), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 18-022-1-Each | In Stock | ₹ 45,091.85 |
18-022-1 - Each
In Stock
Quantity
1
Base Price: ₹ 45,091.85
GST (18%): ₹ 8,116.533
Total Price: ₹ 53,208.383
Antigen
Nkx2.1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
NKX2-1
Gene Alias
AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
7080
Content And Storage
2-8°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
8G7G3/1
Formulation
PBS with 1% BSA and 0.1% sodium azide
Gene Accession No.
P43699
Gene Symbols
NKX2-1
Immunogen
Recombinant full length TTF-1 (Thyroid Transcription Factor 1) protein
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- TTF-1 has been identified as a mediator of thyroid-specific gene transcription, and is involved in the activation of pulmonary-specific genes
- TTF-1 is found in primary lung adenocarcinomas and small cell carcinomas
- TTF-1 is usually absent in breast and colon carcinomas
- TTF-1 monoclonal antibody should be useful in differentiating tumors of lung and non-lung origin
- Lung cancer and thyroid gland tissues have been identified positive for TTF-1 monoclonal antibody concentrate
- This gene encodes a protein initially identified as a thyroid-specific transcription factor
- The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis
- Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer
- Multiple transcript variants encoding different isoforms have been found for this gene.