200020074

Pleiotrophin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Pleiotrophin

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Bovine, Human, Mouse, Rat

Gene Accession No.

P21246, P21782, P63089, P63090

Gene ID (Entrez)

19242, 24924, 280904, 5764

Immunogen

Recombinant Bovine PTN protein, Gly33-Asp168 (Accession #P21782)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

HARP, HBBM, HBBN, HB-GAM, HBGF8, HBGF-8, HBNF, HBNF1, HBNF-1, heparin affin regulatory peptide, heparin affin regulatory protein, heparin binding factor, heparin-binding brain mitogen, Heparin-binding growth factor 8, heparin-binding growth-associated molecule, heparin-binding neurite outgrowth promoting factor, Heparin-binding neurite outgrowth-promoting factor, Heparin-binding neurite outgrowth-promoting factor 1, heparin-binding neurite promoting factor, heparin-binding neurotorphic factor, heparin-binding neutrophic factor, NEGF1, OSF, Osf1, OSF-1, osteoblastic cell factor, Osteoblast-specific factor 1, pleiotrophin, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1), Pleiotrophin (Heparine binding factor, Hbnf, in the mouse), PTN

Gene Symbols

PTN

Isotype

IgG

Purification Method

Protein A

Gene

PTN

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Description

  • Pleiotrophin (PTN) is an 18 kDa secreted heparin and chondroitin-binding protein that is a regulatory cytokine critical to the early development of blood vessels and neurons
  • High PTN serum levels are associated with a variety of solid tumors
  • It was shown that patients with multiple myeloma (MM) also have elevated serum levels of this protein
  • The expression of this protein is very limited in normal adult tissues.