200020191

SHBG Monoclonal Antibody (H3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SHBG

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

ABP, Abpa, androgen binding protein, Androgen binding protein (ABP), SBP, sex hormone binding globulin, Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene), sex hormone-binding globulin, Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Shbg, TeBG, testis-specific androgen-binding protein, Testosterone binding beta globulin, testosterone-binding beta-globulin, testosterone-estradiol-binding globulin, Testosterone-Estradiol-Binding Globulin (TEBG), Testosterone-estrogen-binding globulin

Gene Symbols

SHBG

Isotype

IgG2a κ

Purification Method

Protein A/G

Gene

SHBG

Clone

H3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P04278

Gene ID (Entrez)

6462

Immunogen

Recombinant Human SHBG protein, Gly224-His388 (Accession #P04278)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Description SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses
  • SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers
  • Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes
  • Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.