200020185

Follistatin Monoclonal Antibody (D1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Follistatin

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

activin-binding protein, AL033346, FOL1, Follictatin, Follistatin, follistatin isoform FST317, follistatin-A, FS, FST, Fst-288, RATFOL1

Gene Symbols

Fst

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

Fst

Clone

D1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Rat

Gene Accession No.

P19883, P21674

Gene ID (Entrez)

10468, 24373

Immunogen

Recombinant Human FS protein, Arg35-Val283 (Accession #P19883)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release
  • The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA
  • In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.