PLS3 Monoclonal Antibody (C4), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PLS3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
AI115446, AL024105, BMND18, LOW QUALITY PROTEIN: plastin-3, MGC128570 protein, plastin 3, plastin 3 (T isoform), plastin 3 (T-isoform), plastin 3, T, plastin-3, PLS3, T fimbrin, T plastin, T-fimbrin, T-plastin
Gene Symbols
PLS3
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
PLS3
Clone
C4
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Porcine, Rat
Gene Accession No.
P13797, Q63598
Gene ID (Entrez)
100158187, 5358, 81748
Immunogen
Recombinant Human PLS3 protein, Ala379-Val630 (Accession #P13797)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2)
- Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis
- PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3
- Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.