200020277

ORM1 Monoclonal Antibody (C8), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ORM1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

AGP, AGP 1, Agp1, Agp-1, Agp-2, AGP-A, Agpa1, alpha-1 acid glycoprotein, alpha-1-acid glycoprotein, Alpha-1-acid glycoprotein 1, alpha-1-acid glycoprotein-2, bM340H1.2 (orosomucoid 1), epididymis secretory sperm binding protein Li 153w, HEL-S-153w, OMD, OMD 1, Orm, Orm1, Orm-1, Orosomucoid, orosomucoid 1, orosomucoid-1

Gene Symbols

ORM1

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

ORM1

Clone

C8

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

P02764

Gene ID (Entrez)

24614

Immunogen

Recombinant Rat a1AGP protein, Gln19-Gln186 (Accession #P02764)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • ORM1 is an acute phase plasma protein synthesized by the liver
  • The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation
  • ORM1 is a major acute phase reactant, both in human and in rat
  • In human plasma, ORM1 (44 kDa) is found at levels of 0.5-1.4 mg/mL
  • Its concentration in blood plasma is elevated during acute inflammation, such as trauma, malignancies, myocardial infarction, rheumatoid arthritis, bacterial infections, after major surgery, in cases of chronic pain etc, and can be used for the diagnosis of inflammatory conditions.