LRP1 Monoclonal Antibody (D3), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
LRP1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
A2MR, AI316852, alpha 2-macroglobulin receptor, alpha-2-macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, b2b1554Clo, CD91, FLJ16451, IGFBP3R, LDL receptor related protein 1, lipoprotein receptor-related protein, low density lipoprotein receptor-related protein 1, low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Lrp, Lrp1, LRP-1, LRP1A, LRP-515, LRP-85, LRPICD, MGC88725, Prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor
Gene Symbols
LRP1
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
LRP1
Clone
D3
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Rat
Gene Accession No.
Q07954
Gene ID (Entrez)
299858, 4035
Immunogen
Recombinant Human LRP1 protein, Val4441-Ala4544 (Accession #Q07954)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells
- In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients
- Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.