3844574
CD11c Hamster anti-Mouse, PE-Cy7, Clone: HL3, BD
Hamster Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11c
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Hamster
Target Species
Mouse
Immunogen
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
HL3
Applications
Flow Cytometry
Conjugate
PE-Cyanine7
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1 λ2
Purification Method
Affinity Purified
Description
Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
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Description
- The HL3 antibody reacts with the integrin αx chain of gp150, 95 (CD11c/CD18) which is expressed on dendritic cells and CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and is upregulated on IEL and lymph-node T cells following in vivo activation
- CD11c is also found on human NK cells
- Although its expression on mouse NK cells is not published, we have detected CD11c on mouse splenic NK cells
- Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c
- CD11c plays a role in binding of iC3b
- Host Species: Hamster Clone: HL3 Isotype: IgG1, λ2 Species Reactivity: Mouse Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes Flow Cytometry