4541078

CDw75 Ab-1 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence and flow cytometry experiments with Epredia™ CDw75 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

CDw75 Ab-1

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Target Species

Human

Isotype

IgM κ

Clone

LN1

Classification

Monoclonal

Host Species

Mouse

Research Discipline

B-Cell

Immunogen

Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes

Primary or Secondary

Primary

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Description

  • CDw75 is a neuraminidase-sensitive sialoprotein, present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas
  • LN1 reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin's disease
  • LN1 is shown to be a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues
  • Host Species: Mouse Clone: LN1 Isotype: IgM/κ Species Reactivity: Human
  • Does not react with rat
  • Others not known Epitope: Not determined Immunogen: Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes Molecular Weight: 53 and 87 kDa Positive Control: Lymph node or tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence Flow Cytometry