4546027
CD45/T200/LCA Ab-2 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence, and flow cytometry experiments.
Manufacturer: Fischer Scientific
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Antigen
CD45/T200/LCA Ab-2
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Immunogen
PD7/26/16: human peripheral blood lymphocytes maintained in T cell growth factor. 2B11: isolated neoplastic cells from T cell lymphoma.
Clone
PD7/26/16 + 2B11
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Oncogenesis
Primary or Secondary
Primary
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Description
- CD45 leucocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues
- The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals
- Antibody to CD45 is useful in differential identification of lymphoid tumors from non-hematopoietic undifferentiated neoplasms
- Host Species: Mouse Clone: PD7/26/16 + 2B11 Isotype: IgG1/κ Species Reactivity: Human
- Does not react with rat and dog
- Others not known Epitope: Not determined Immunogen: PD7/26/16: human peripheral blood lymphocytes maintained in T-cell growth factor
- 2B11: isolated neoplastic cells from T-cell lymphoma Molecular Weight: 220, 205, 190, 180 kDa Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence Flow Cytometry