4544012
Epredia™ Lab Vision™ Cytokeratin 15 Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Ensure accurate, reproducible results in immunofluorescence applications with Epredia™ Cytokeratin 15 Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Cytokeratin 15 Ab-1
Applications
Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Cytoskeletal Protein
Immunogen
A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15
Primary or Secondary
Primary
Clone
LHK15
Classification
Monoclonal
Form
Concentrated
Regulatory Status
RUO
Target Species
Bovine, Human, Mouse, Rat
Isotype
IgG2a κ
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Description
- Keratin 15 is a type I keratin without a defined type II partner
- Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail
- Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars
- Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype
- Host Species: Mouse Clone: LHK15 Isotype: IgG2a/κ Species Reactivity: Human, Cow, Mouse and Rat
- Others not known
- Epitope: C-terminal Immunogen: A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15 Positive Control: Skin Cellular Localization: Cytoplasmic Recommended for: Immunofluorescence Note: USA: RUO; Int'l: RUO