4551949
Epredia™ Lab Vision™ MAP 2a,b (Microtubule-Associated Protein) Ab-2, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ MAP 2a,b (Microtubule-Associated Protein) Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
MAP 2a,b (Microtubule-Associated Protein) Ab-2
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Clone
AP20
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Neuroscience
Immunogen
Bovine brain microtubule associated protein 2
Primary or Secondary
Primary
Related Products
Description
- Microtubule Associated Protein 2 exists in two high molecular weight forms (2a & 2b) and a low molecular weight form
- The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene
- Ab-2 is highly specific to MAP2a,b and shows no cross-reaction with MAP1, MAP5, tubulin, or tau
- Ab-2 reacts with dendrites and cell bodies of neurons but not with the neuronal processes
- It does not react with the low molecular weight (70kDa) form (2c) of MAP2
- It is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's
- Host Species: Mouse Clone: AP20 Isotype: IgG1 Species Reactivity: Human
- Others not known
- Epitope: aa 997-1332 Immunogen: Bovine brain microtubule associated protein 2 Molecular Weight: ∽280kDa Doublet Positive Control: Human glioblastoma T98G cells or brain Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Note: USA: RUO; Int'l: RUO