4551950

MAP 2a,b,c (Microtubule-Associated Protein) Ab-3 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with the Epredia™ MAP 2a,b,c (Microtubule-Associated Protein) Ab-3, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

MAP 2a,b,c (Microtubule-Associated Protein) Ab-3

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Regulatory Status

IVD

Target Species

Bovine, Human, Quail, Rat, Xenopus species

Isotype

IgG1

Clone

AP18

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Neuroscience

Immunogen

Bovine brain microtubule associated protein 2

Primary or Secondary

Primary

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Description

  • Microtubule Associated Protein 2 exists in two high molecular weight forms (2a & 2b) and a low molecular weight form
  • The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene
  • Ab-3 is specific to phosphprylated form of MAP2a,b,c and shows no cross-reaction with other MAPs, tau, and tubulin
  • Ab-3 reacts with dendrites and cell bodies of neurons
  • It is useful in studies of neuron structure in normal and malignant brain tissue and in Alzheimer's
  • Host Species: Mouse Clone: AP18 Isotype: IgG1 Species Reactivity: Human, Cow, Rat, Xenopus , Quail
  • Others not known
  • Epitope: aa 1-151 Immunogen: Bovine brain microtubule associated protein 2 Molecular Weight: ∽280kDa doublet and a 70kDa singlet Positive Control: IMR-5 or T98G human glioblastoma cells or brain Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence