4559204
Epredia™ Lab Vision™ Prostate Specific Antigen (PSA), Rabbit Monoclonal Antibody
Employ part of a comprehensive antibody portfolio Epredia™ Prostate Specific Antigen (PSA), Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
Manufacturer: Fischer Scientific
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Antigen
Prostate Specific Antigen (PSA)
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
ASR
Immunogen
A synthetic peptide corresponding to residues near the C-terminus of human PSA
Clone
EP1588Y
Classification
Monoclonal
Host Species
Rabbit
Research Discipline
Cancer and Tumor Biology
Primary or Secondary
Primary
Related Products
Description
- PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid
- PSA can be detected in the sera of patients with prostatic carcinoma
- It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT)
- A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia
- PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics
- Host Species: Rabbit Clone: EP1588Y Species Reactivity: Human
- Others not known
- Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human PSA Molecular Weight: 34kDa Positive Control: Normal prostate or prostate carcinoma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)