CD88 (C5aR1) Monoclonal Antibody (S5/1), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-088-842-Each-of-1 | In Stock | ₹ 35,689.00 |
46-088-842 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,689.00
GST (18%): ₹ 6,424.02
Total Price: ₹ 42,113.02
Antigen
CD88 (C5aR1)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P21730
Gene Symbols
C5AR1
Immunogen
BSA-Conjugated Peptide aa. 1-31
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
S5/1
Conjugate
PerCP-eFluor 710
Gene
C5AR1
Gene Alias
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
728
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- This S5/1 MAb recognizes human CD88 also known as C5aR1
- C5aR1 is a complement receptor widely expressed on cells of the myeloid lineage
- Clone S5/1 has been reported to block C5a binding
- CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
- C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
- CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
- Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
- CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
- Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.