CD88 (C5aR1) Monoclonal Antibody (20/70), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-088-282-Each-of-1 | In Stock | ₹ 32,485.00 |
46-088-282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
CD88 (C5aR1)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
P30993
Gene Symbols
C5AR1
Immunogen
RBL-2H3 transfected cells expressing murine C5aR
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
20/70
Conjugate
PerCP-eFluor 710
Gene
C5AR1
Gene Alias
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Host Species
Rat
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12273
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- Description: This 20/70 monoclonal antibody recognizes mouse CD88 also known as C5aR1
- CD88 is a complement receptor widely expressed on cells of the myeloid lineage
- Clone 20/70 has been reported to block the binding of C5a to murine CD88
- Applications Reported: This 20/70 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 20/70 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- PerCP-eFluor 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5
- We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative
- Please make sure that your instrument is capable of detecting this fluorochrome
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- 00-8222-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
- CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
- C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
- CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
- Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
- CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
- Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.