50-112-2521

CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2521-Each-of-1 In Stock ₹ 14,596.00

50-112-2521 - Each of 1

₹ 14,596.00

In Stock

Quantity

1

Base Price: ₹ 14,596.00

GST (18%): ₹ 2,627.28

Total Price: ₹ 17,223.28

Antigen

CD119 (IFN gamma Receptor 1)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P15261

Gene Symbols

IFNGR1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15979

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2E2

Conjugate

Biotin

Gene

IFNGR1

Gene Alias

antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar

Host Species

Armenian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description: The monoclonal antibody 2E2 recognizes mouse CD119 also known as IFN gamma receptor1
  • CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor
  • The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit
  • The receptor is involved in host defense and expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types
  • Applications Reported: This 2E2 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2E2 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0.2 μm post-manufacturing filtered
  • This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor
  • Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2
  • A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection
  • In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.