F4/80 Monoclonal Antibody (BM8), eFluor™ 506, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4965-Each-of-1 | In Stock | ₹ 14,507.00 |
50-112-4965 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,507.00
GST (18%): ₹ 2,611.26
Total Price: ₹ 17,118.26
Antigen
F4/80
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q61549
Gene Symbols
ADGRE1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13733
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
BM8
Conjugate
eFluor 506
Gene
ADGRE1
Gene Alias
ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
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Description
- Description: The eBio299Arm monoclonal antibody is useful as an isotype control immunoglobulin
- Applications Reported: This eBio299Arm antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBio299Arm antibody has been tested by flow cytometric analysis of normal human peripheral blood cells and mouse splenocytes
- Use the isotype control at the same concentration as the experimental antibody
- eFluor™ 506 can be excited with the violet laser line (405 nm) and emits at 506 nm
- We recommend using a 510/20 band pass filter, or equivalent
- Please make sure that your instrument is capable of detecting this fluorochrome
- Excitation: 405 nm; Emission: 506 nm; Laser: Violet Laser
- Filtration: 0.2 μm post-manufacturing filtered
- F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1)
- Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation
- The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen
- F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node
- The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.