NKG2AB6 Monoclonal Antibody (16a11), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9072-Each-of-1 | In Stock | ₹ 32,663.00 |
50-112-9072 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,663.00
GST (18%): ₹ 5,879.34
Total Price: ₹ 38,542.34
Antigen
NKG2AB6
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
0
Gene Symbols
Klrc1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16641
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
16a11
Conjugate
PerCP-eFluor 710
Gene
Klrc1
Gene Alias
CD159 antigen-like family member A; CD159A; C-lectin type II protein; Cluster of Differentiation 159a; killer cell lectin like receptor C1; killer cell lectin-like receptor subfamily C, member 1; Klrc1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; rNKG2A
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The 16a11 monoclonal antibody reacts with the mouse NKG2A^B6
- NKG2 molecules belong to a C-type lectin-like family of cell surface receptors expressed by mouse NK and NKT cell lineages
- NKG2 molecules form heterodimeric complexes with CD95 and are responsible for recognition of non-classical MHC class I antigen Qa-1
- This antibody reacts with the C57Bl/6 mouse strain, but does not react with the BALB/c or 129 mouse strains
- When co-staining with NKG2A/C/E clone 20d5, it is important to stain for NKG2A^B6 first then subsequently with NKG2A/C/E, as steric hindrance has been observed if co-stained concurrently
- Applications Reported: This 16a11 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 16a11 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5
- We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
- They can also regulate specific humoral and cell-mediated immunity
- The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells
- This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain
- This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells
- The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12
- Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.