50-113-7707

NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7707-Each-of-1 In Stock ₹ 23,496.00

50-113-7707 - Each of 1

₹ 23,496.00

In Stock

Quantity

1

Base Price: ₹ 23,496.00

GST (18%): ₹ 4,229.28

Total Price: ₹ 27,725.28

Antigen

NKG2A/NKG2C/NKG2E

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

0

Gene Symbols

Klrc1, Klrc2, Klrc3

Immunogen

epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

20d5

Conjugate

PE

Gene

Klrc3

Gene Alias

CD159a; cd159c; cd159e; Cluster of Differentiation 159a; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; Klrc1; Klrc2; Klrc3; natural killer cell group 2E cell receptor; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; NKG2C; Nkg2e

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

16641, 16642, 58179

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
  • They can also regulate specific humoral and cell-mediated immunity
  • The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells
  • This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain
  • This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells
  • The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12
  • Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.