50-112-9323

Somatostatin Monoclonal Antibody (ICDCLS), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each 50-112-9323-Each In Stock ₹ 13,763.85

50-112-9323 - Each

₹ 13,763.85

In Stock

Quantity

1

Base Price: ₹ 13,763.85

GST (18%): ₹ 2,477.493

Total Price: ₹ 16,241.343

Antigen

Somatostatin

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P60041, P60042, P61278

Gene Symbols

SST

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20604, 24797, 6750

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

ICDCLS

Conjugate

Unconjugated

Gene

SST

Gene Alias

Antrin; Growth hormone release-inhibiting factor; Neuronostatin; NST; preprosomatostatin; prepro-somatostatin; SMST; SOM; Somatostatin; somatostatin 28; somatostatin-14; Somatostatin-28; somatotropin release-inhibiting factor; SRIF; SS; SS-14; SS-28; Sst; SST-14

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The monoclonal antibody ICDCLS recognizes human, mouse, and rat Somatostatin
  • Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or somatotrophin release-inhibiting factor (SRIF), is a peptide hormone with two active forms (14 and 28 amino acids) produced by alternative cleavage of a single preproprotein
  • Somatostatin is secreted by the delta cells of the islet of Langerhans in the pancreas as well as by the hypothalamus and intestine
  • Somatostatin has a variety of functions, such as regulating the endocrine system and affecting neurotransmission and cell proliferation
  • Somatostatin also inhibits the release of numerous secondary hormones, such as insulin and glucagon
  • Somatostatin can be used to identify medium size aspiny neurons in the striatum, cortex, and hippocampus
  • Expression of somatostatin is present in hyperplasia of the pancreatic islets as well as islet cell tumors such as somatostatinomas
  • Applications Reported: This ICDCLS antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, and microscopy
  • Applications Tested: This ICDCLS antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 0.1 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene
  • Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors
  • This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract
  • Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.