Lambda light chain Monoclonal Antibody (1-155-2), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-50-Each-of-1 | In Stock | ₹ 24,653.00 |
50-113-50 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,653.00
GST (18%): ₹ 4,437.54
Total Price: ₹ 29,090.54
Antigen
Lambda light chain
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P01701, P0CG04
Gene Symbols
IGL, IGLC1, IGLV, IGLV1-51
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
28820, 3535, 3537, 3546
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1-155-2
Conjugate
PE
Gene
IGLV1-51
Gene Alias
Bence Jones Protein; BJP; Clambda1; Ig lambda chain V-I region BL2; IgL; Igl@; IGLC; IGLC 1/2/3; IGLC1; Igl-C1; IGLL5; IGLV; IGLV@; immmunoglobulin lambda light chain variable region; Immunoglobulin L; immunoglobulin lambda chain complex; immunoglobulin lambda constant 1; immunoglobulin lambda constant 7; immunoglobulin lambda light chain; immunoglobulin lambda light chain constant region; immunoglobulin lambda light chain V-J region; immunoglobulin lambda variable cluster; Lambda LC; lambda-immunoglobulin; LOC100060608; Mcg Marker; Paraprotein
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The monoclonal antibody 1-155-2 recognizes the lambda light chain of human immunoglobulin
- Approximately 22-kDa, the Ig lambda chain is comprised of one variable and one constant region
- Two lambda chains together with the heavy chain comprise the whole Ig structure
- Expression of Ig lambda is typically found in less than half of B lymphocytes, and has been associated with neoplastic lymphomas
- Applications Reported: This 1-155-2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1-155-2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa)
- Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region
- The ratio of kappa to lambda is 70:30
- Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas
- Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.