50-130-76
EOMES Monoclonal Antibody (21Mags8), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-130-76-Each-of-1 | In Stock | ₹ 25,721.00 |
50-130-76 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,721.00
GST (18%): ₹ 4,629.78
Total Price: ₹ 30,350.78
Antigen
EOMES
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O54839, O95936
Gene Symbols
Eomes
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13813, 8320
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Western Blot
Clone
21Mags8
Conjugate
Unconjugated
Gene
Eomes
Gene Alias
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This 21Mags8 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2)
- Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates
- In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells
- Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R
- Note: For detection of mouse Eomes, we recommend 12-4875 and 51-4875 and for detection of human Eomes, we recommend 51-4877 due to the brighter staining intensity of these products compared to clone 21Mags8
- Applications Reported: This 21Mags8 antibody has been reported for use in flow cytometric analysis, and immunoblotting (WB)
- Applications Tested: This 21Mags8 antibody has been tested by western blot analysis of mouse splenocytes
- As a starting concentration, this antibody can be used at 2 μg/mL
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box
- T-box genes encode transcription factors involved in the regulation of developmental processes
- A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation
- TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.