PIPA589267

HNMT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA589267-Each-of-1 In Stock ₹ 46,502.50

PIPA589267 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

HNMT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Hnmt

Gene Alias

1500031F01Rik, AI788969, histamine N-methyltransferase, Hmt, Hnmt, HNMT-S1, HNMT-S2, MRT51

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140483, 3176

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P50135, Q91VF2

Gene Symbols

Hnmt

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human HNMT (NP_0088261)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MASSMRSLFS DHGKYVESFR RFLNHSTEHQ CMQEFMDKKL PGIIGRIGDT KSEIKILSIG GGAGEIDLQI LSKVQAQYPG VCINNEVVEP SAEQIAKYKE LVAKTSNLEN VKFAWHKETS SEYQSRMLEK KELQKWDFIH MIQMLYYVKD IPATLKFFHS LLGTNAKMLI IVVSGSSGWD KLWKKYGSRF PQDDLCQYIT SDDLTQMLDN LGLKYECYDL LSTMDISDCF IDGNENGDLL WDFLTETCNF NATAPPDLRA ELGKDLQEPE FSAKKEGKVL FNNTLSFIVI EA; Positive Samples: HT-29, HepG2, HeLa, Mouse liver, Mouse kidney, Mouse brain; Cellular Location: Cytoplasm In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase
  • HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor
  • In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system
  • A common genetic polymorphism affects the activity levels of this gene product in red blood cells.