50-155-7272
SMAR1/BANP Rabbit anti-Human, Mouse, Rat, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7272-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-7272 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
SMAR1/BANP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BANP
Gene Alias
BEND1, SMAR1, SMARBP1; BEN domain-containing protein 1; protein BANP; scaffold/matrix-associated region-1-binding protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292064, 53325, 54971
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q8N9N5, Q8VBU8
Gene Symbols
BANP
Immunogen
Between 425 and C-term
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen
- BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest
- p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop
- BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling
- Furthermore, BANP can modulate NF-kappa-B transactivation and can inhibit tumorigenesis by regulating NF-kappa-B target genes
- Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.