50-155-7274
SMAR1/BANP Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7274-Each-of-1 | In Stock | ₹ 12,384.35 |
50-155-7274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
SMAR1/BANP
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q8N9N5, Q8VBU8
Gene Symbols
Banp
Immunogen
Between 425 and C-term
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene
BANP
Gene Alias
BEND1, SMAR1, SMARBP1; BEN domain-containing protein 1; protein BANP; scaffold/matrix-associated region-1-binding protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292064, 53325, 54971
Content And Storage
4° C
Form
Liquid
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predict BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen
- BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest
- p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop
- BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling
- Furthermore, BANP can modulate NF-kappa-B transactivation and can inhibit tumorigenesis by regulating NF-kappa-B target genes
- Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.